Anticholinergic drugs may induce dementia

A group of English researchers has published an interesting study funded by the Alzheimer Society, which analyzes the long-term effects of some major drugs in patients. Specifically, the team has assessed drugs for the treatment of major conditions, such as depression, Parkinson’s disease and prostate cancer, observing that those drugs can induce dementia. The research has analyzed a sample of 41,000 patients over 65 with dementia, comparing it to another sample of 284,000 patients without dementia. The study demonstrates that patients who take anticholinergics are 30% more subject to dementia over a 15-year span. The researchers have not clarified by which mechanism anticholinergics induce dementia, however it is fairly clear that a stage in the procedure induces inflammation.

(Source: BMJ)